Association of genes to genetically inherited diseases using data mining

@article{PerezIratxeta2002AssociationOG,
  title={Association of genes to genetically inherited diseases using data mining},
  author={C. Perez-Iratxeta and P. Bork and M. Andrade},
  journal={Nature Genetics},
  year={2002},
  volume={31},
  pages={316-319}
}
  • C. Perez-Iratxeta, P. Bork, M. Andrade
  • Published 2002
  • Biology, Medicine
  • Nature Genetics
  • Although approximately one-quarter of the roughly 4,000 genetically inherited diseases currently recorded in respective databases (LocusLink, OMIM) are already linked to a region of the human genome, about 450 have no known associated gene. Finding disease-related genes requires laborious examination of hundreds of possible candidate genes (sometimes, these are not even annotated; see, for example, refs 3,4). The public availability of the human genome draft sequence has fostered new strategies… CONTINUE READING
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