Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4.

@article{Murphy2009AssociationOG,
  title={Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4.},
  author={Gwen Murphy and Jacinta Thornton and Ross McManus and Niall Swan and Barbara Ryan and David J. Hughes and Colm O'mor{\'a}in and Maria O'sullivan},
  journal={European journal of gastroenterology & hepatology},
  year={2009},
  volume={21 6},
  pages={630-5}
}
OBJECTIVES This study aimed to investigate if single nucleotide polymorphisms (SNPs) in a series of inflammatory genes were associated with the development of the most common pathologies thought to precede gastric cancer development namely; Helicobacter pylori (H. pylori)-associated gastritis and intestinal metaplasia. METHODS A total of 250 patients were genotyped for 11 SNPs in the IL-1B, IL-1RN, TNF, TLR4 and IL-10 genes. The study population comprised H. pylori uninfected ('normal… CONTINUE READING
18 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…