Association of gangliosides with the lymphocyte plasma membrane studied using radiolabels and spin labels.

@article{Sharom1986AssociationOG,
  title={Association of gangliosides with the lymphocyte plasma membrane studied using radiolabels and spin labels.},
  author={Frances Jane Sharom and Tori Ross},
  journal={Biochimica et biophysica acta},
  year={1986},
  volume={854 2},
  pages={287-97}
}
Gangliosides are known to act as potent suppressors of lectin-stimulated lymphocyte activation when added to the culture medium. Since this effect may be mediated via ganglioside association with (or insertion into) the plasma membrane, we have used 3H- and spin-labelled derivatives of mixed gangliosides to probe the nature of this interaction. Gangliosides… CONTINUE READING