Association of galectin-3 expression with melanoma progression and prognosis.

  title={Association of galectin-3 expression with melanoma progression and prognosis.},
  author={Ewan Russell Stewart Brown and Tamasin N Doig and Niall Anderson and Thomas Brenn and Val R Doherty and Yan Xu and John M. S. Bartlett and John F. Smyth and David W. Melton},
  journal={European journal of cancer},
  volume={48 6},
AIMS Galectin-3 plays an important role in adhesion, proliferation, differentiation, angiogenesis and metastasis in multiple tumours. To investigate the role of galectin-3 in melanoma pathogenesis we examined the expression of galectin-3 in melanocytic lesions and analysed the correlation between galectin-3 expression and clinicopathologic factors including patient survival and BRAF mutation status. METHODS We evaluated the expression of galectin-3 in 53 cases of benign naevi, 31 cases of… CONTINUE READING


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