Association of frequent consumption of fatty fish with prostate cancer risk is modified by COX-2 polymorphism.

@article{Hedelin2007AssociationOF,
  title={Association of frequent consumption of fatty fish with prostate cancer risk is modified by COX-2 polymorphism.},
  author={Maria Hedelin and Ellen T. Chang and Fredrik Wiklund and Rino Bellocco and Asa Klint and J. Patrik Adolfsson and Katarina Shahedi and J Xu and Hans-olov Adami and Henrik Gr{\"o}nberg and Katarina Augustsson B{\"a}lter},
  journal={International journal of cancer},
  year={2007},
  volume={120 2},
  pages={398-405}
}
Dietary intake of marine fatty acids from fish may protect against prostate cancer development. We studied this association and whether it is modified by genetic variation in cyclooxygenase (COX)-2, a key enzyme in fatty acid metabolism and inflammation. We assessed dietary intake of fish among 1,499 incident prostate cancer cases and 1,130 population controls in Sweden. Five single nucleotide polymorphisms (SNPs) were identified and genotyped in available blood samples for 1,378 cases and 782… CONTINUE READING

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