Association of fetuin-a with incident diabetes mellitus in community-living older adults: the cardiovascular health study.

@article{Ix2012AssociationOF,
  title={Association of fetuin-a with incident diabetes mellitus in community-living older adults: the cardiovascular health study.},
  author={Joachim H. Ix and Mary Lou Biggs and Kenneth Jay Mukamal and Jorge R Kizer and Susan J. Zieman and David S Siscovick and Dariush Mozzaffarian and Majken Karoline Jensen and Lauren Nelson and Neil Bertrand Ruderman and Luc Djouss{\'e}},
  journal={Circulation},
  year={2012},
  volume={125 19},
  pages={2316-22}
}
BACKGROUND The liver-secreted protein fetuin-A induces peripheral insulin resistance in vitro. In a pilot study, we observed that higher fetuin-A levels were associated with diabetes mellitus in older persons. However, this finding has not been confirmed in large cohorts. We sought to confirm the association of fetuin-A with incident diabetes mellitus in older persons and to determine whether the association differs by age, sex, and race and among persons with cardiovascular disease (CVD… CONTINUE READING

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