Association of estrogen receptors’ promoter methylation and clinicopathological characteristics in Iranian patients with breast cancer

@inproceedings{Loghmani2014AssociationOE,
  title={Association of estrogen receptors’ promoter methylation and clinicopathological characteristics in Iranian patients with breast cancer},
  author={Hora Loghmani and Mehrdad Noruzinia and Hossein Abdul Tehrani and Mahdieh Taghizadeh and Karbassian Mohammad Hamid},
  year={2014}
}
Estrogens play a substantial role in the proliferation, progression and treatment of breast cancer by binding with two estrogen receptors, alpha and beta (ER�. and ER�� ). Resistance to endocrine therapy is a major problem in the treatment of breast cancers and, in some cases, may be related to loss of ER gene expression. We have already showed that ER�. methylation occurs in high frequency and may be one of the important mechanisms for ER�. gene silencing in a subset of Iranian primary… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Five common cancers in Iran.

VIEW 1 EXCERPT
HIGHLY INFLUENTIAL

Breast cancer in Iran: an epidemiological review.

  • The breast journal
  • 2007
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Epigenotyping in Peripheral Blood Cell DNA D ow nl oa de d fr om lr r. m od ar es .a c. ir at 1 :3 3 IR D T o n S at ur da y A ug us t 3 rd 2 01 9 et al

M Widschwendter, S Apostolidou, E Raum, D Rothenbacher, H Fiegl
  • 2008
VIEW 1 EXCERPT