Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis.

@article{Wu2006AssociationOE,
  title={Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis.},
  author={Jie Wu and Yong Qiu and Le Zhang and Qiang Qiang Sun and Xu-sheng Qiu and Yongxiong He},
  journal={Spine},
  year={2006},
  volume={31 10},
  pages={1131-6}
}
STUDY DESIGN A case-control study is presented. OBJECTIVE To investigate the association of estrogen receptor gene polymorphisms with adolescent idiopathic scoliosis (AIS) risk. SUMMARY OF BACKGROUND DATA Previous studies have shown that genetic factors are important in the pathogenesis of idiopathic scoliosis. Only 1 publication suggested that XbaI site polymorphism was associated with curve severity of idiopathic scoliosis. However, to our knowledge, the relationship of estrogen receptor… CONTINUE READING