Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme.

  title={Association of elevated glial expression of interleukin-1beta with improved survival in patients with glioblastomas multiforme.},
  author={Emmanuel Cuny and Hugues Loiseau and Guillaume Penchet and E. Ellie and Josette Arsaut and Anne Vital and Philippe Vincendeau and Jacques Demotes-Mainard},
  journal={Journal of neurosurgery},
  volume={96 2},
OBJECT The aim of this study was to investigate the association of interleukin-1beta (IL-1beta) expression with improved survival in patients with glioblastomas multiforme (GBMs). Immune and vascular host-tumor interactions play a pivotal role in the control of tumor development, and inflammatory mechanisms may participate in the host's defense against tumor cells. Expression of proinflammatory cytokines and of inducible nitric oxide synthase (iNOS) has been noted in various types of malignant… 

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