Association of doxycycline use with the development of gastroenteritis, irritable bowel syndrome and inflammatory bowel disease in Australians deployed abroad
@article{Lee2013AssociationOD, title={Association of doxycycline use with the development of gastroenteritis, irritable bowel syndrome and inflammatory bowel disease in Australians deployed abroad}, author={T W Lee and L Russell and Min Deng and Peter R. Gibson}, journal={Internal Medicine Journal}, year={2013}, volume={43} }
The risks are unknown for developing chronic gastrointestinal illness when personnel are relocated short term to other countries and when taking antibiotic prophylaxis in areas where malaria is endemic.
17 Citations
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A nested case–control study that provides important evidence of an association between antibiotic use and the subsequent development of FGIDs, which has biological plausibility, and serves as yet another reason for judicious use of these drugs.
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An update on the evidence surrounding the adverse effects of isotretinoin is provided, and practical strategies to prevent and manage these adverse effects are discussed.
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It is vital that the clinician understand the pros and cons of each tetracycline agent so as to optimally serve the acne population.
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- Medicine, BiologyDermatologic therapy
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Weight‐based dosing protocols and the impact of food intake, including high‐fat meals, on the absorption, and clinical efficacy of sarecycline, a novel oral narrow‐spectrum third‐generation tetracycline‐class antibiotic approved by the Food and Drug Administration for acne vulgaris treatment are investigated.
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There was no association between UC or CD and overall prior use of antibiotics, though prior useof metronidazole and quinolones was associated with a slightly increased risk of CD.
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The narrower spectrum of antibacterial activity of sarecycline, which specifically targets C. acnes and some Gram-positive bacteria with little or no activity against Gram-negative bacteria, suggests not only the potential for reduced emergence of antibiotic-resistant bacterial strains but also less disruption of the human gut microflora.
Prevention of Malaria in Travelers: Bite Avoidance and Chemoprophylactic Measures
- MedicineCurrent Treatment Options in Infectious Diseases
- 2013
Atovaquone-proguanil is highly effective in preventing Plasmodium falciparum malaria, is well-tolerated, and is active against both liver and blood stages, which decreases the length of time required for post-travel prophylaxis, and alternative agents include doxycycline and mefloquine.
Mechanisms of Bacterial Resistance
- Medicine
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In 1900, the three leading causes of death were pneumonia, tuberculosis, and diarrhea with enteritis. Today, due to the control of infectious diseases over the last century, the leading causes of…
Antibiotics Associated With Increased Risk of New-Onset Crohn’s Disease But Not Ulcerative Colitis: A Meta-Analysis
- MedicineThe American Journal of Gastroenterology
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Exposure to antibiotics appears to increase the odds of being newly diagnosed with Crohn’s disease but not UC, and this risk is most marked in children diagnosed with CD.
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