Association of different allelic forms of group specific component with susceptibility to and clinical manifestation of human immunodeficiency virus infection.

@article{Eales1987AssociationOD,
  title={Association of different allelic forms of group specific component with susceptibility to and clinical manifestation of human immunodeficiency virus infection.},
  author={L J Eales and Keith E Nye and Jacqueline M Parkin and Jonathan Weber and Sylvia Forster and Julie R Harris and Anthony J Pinching},
  journal={Lancet},
  year={1987},
  volume={1 8540},
  pages={999-1002}
}
The distribution of phenotypes of the group specific component (Gc) was examined in 203 homosexuals at risk of infection or infected by the human immunodeficiency virus and compared with that in 50 randomly selected homosexuals and 122 healthy male heterosexual seronegative controls. 30.2% of patients with the acquired immunodeficiency syndrome (AIDS) were homozygous for Gc 1 fast (Gc 1f) compared with 0.8% of controls (p less than 0.0001); patients with other clinical manifestations of HIV… CONTINUE READING

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