Association of cytochrome P450 1B1 haplotypes with head and neck cancer risk.

Abstract

Genetic polymorphisms have been reported in several cytochrome P450 (CYP) genes, including CYP1B1 which metabolically activates procarcinogens present in tobacco to carcinogenic intermediates. This study used a case-control approach in North Indian population to determine associations between genetic variants in CYP1B1 and risk of Head and Neck Squamous… (More)
DOI: 10.1002/em.22098

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