Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study.

@article{Morrison2013AssociationOC,
  title={Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study.},
  author={Jonathan J Morrison and James D Ross and Joseph Dubose and Jan O. Jansen and Mark J. Midwinter and Todd E. Rasmussen},
  journal={JAMA surgery},
  year={2013},
  volume={148 3},
  pages={
          218-25
        }
}
OBJECTIVE To quantify the impact of fibrinogen-containing cryoprecipitate in addition to the antifibrinolytic tranexamic acid on survival in combat injured. DESIGN Retrospective observational study comparing the mortality of 4 groups: tranexamic acid only, cryoprecipitate only, tranexamic acid and cryoprecipitate, and neither tranexamic acid nor cryoprecipitate. To balance comparisons, propensity scores were developed and added as covariates to logistic regression models predicting mortality… CONTINUE READING
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