Association of complement factor H polymorphisms with exudative age-related macular degeneration.

@article{Chen2006AssociationOC,
  title={Association of complement factor H polymorphisms with exudative age-related macular degeneration.},
  author={Li Jia Chen and David T. L. Liu and Pancy O. S. Tam and Wai Man Chan and Ke Liu and Kelvin Kam-Lung Chong and Dennis Shun Chiu Lam and Chi Pui Pang},
  journal={Molecular vision},
  year={2006},
  volume={12},
  pages={1536-42}
}
PURPOSE Variants in the complement factor H (CFH) gene have been reported to be associated with age-related macular degeneration (AMD). We conducted a case-control association study to investigate the association of 6 single nucleotide polymorphisms (SNPs) in CFH with exudative AMD in the Chinese population. METHODS We recruited 163 cases and 244 controls, all ethnic Chinese, with complete ophthalmic examination including fundus investigation. Cigarette smoking was recorded. Six SNPs (dbSNP… CONTINUE READING
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