Association of complement C4 and HLA-DR alleles with systemic lupus erythematosus in Koreans.

@article{Hong1994AssociationOC,
  title={Association of complement C4 and HLA-DR alleles with systemic lupus erythematosus in Koreans.},
  author={Gi Hyun Hong and H Y Kim and Fujio Takeuchi and Kazuhisa Nakano and Hirofumi Yamada and Kunio Matsuta and Hui-xing Han and Katsushi Tokunaga and Keisuke Ito and Kyoung Sook Park},
  journal={The Journal of rheumatology},
  year={1994},
  volume={21 3},
  pages={442-7}
}
OBJECTIVE To examine the association of complement C4 and HLA-DR to systemic lupus erythematosus (SLE) susceptibility in Korea. METHODS Complement C4 protein typing was carried out by immunofixation and immunoblotting methods using EDTA-plasma from 60 patients with SLE and 72 healthy controls. Restriction fragment length polymorphism analysis of C4 genes was also carried out using TaqI or HindIII for restriction enzymes. HLA-DR was determined by polymerase chain reaction amplification with… CONTINUE READING

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