Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.

@article{Bakken2012AssociationOC,
  title={Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.},
  author={Trygve E Bakken and J. Cooper Roddey and Srdjan Djurovic and Natacha Akshoomoff and David G. Amaral and Cinnamon S. Bloss and Barbara J. Casey and Linda Chang and Thomas M Ernst and Jeffrey R. Gruen and Terry L. Jernigan and Walter E Kaufmann and Tal Kenet and David N. Kennedy and Joshua M. Kuperman and Sarah S. Murray and Elizabeth R. Sowell and Lars Morten Rimol and Morten Mattingsdal and Ingrid Melle and Ingrid Agartz and Ole Andreas Andreassen and Nicholas J. Schork and Anders M. Dale and Michael W Weiner and Paul S. Aisen and Ronald J. Petersen and Clifford R. Jack and William Jagust and John Q. Trojanowki and Arthur W. Toga and Laurel A. Beckett and Robert C Green and Andrew J. Saykin and John C. Morris and Enchi Liu and Tom Montine and Anthony Gamst and Ronald G. Thomas and Michael Donohue and Sarah Walter and Devon Gessert and Tamie Miura Sather and Danielle Harvey and John Kornak and Matthew A. Bernstein and Joel P. Felmlee and Nick C. Fox and P. C. Thompson and Norbert W. Schuff and G Alexandrovich Alexander and Charles S. Decarli and Dan Bandy and Robert A. Koeppe and Norm Foster and Eric M. Reiman and Kewei Chen and C. A. Mathis and Nigel J. Cairns and Lisa Taylor-Reinwald and Les M Shaw and Virginia M.-Y. Lee and Magdalena Korecka and Karen Shichman Crawford and Scott Neu and Tatiana M. Foroud and Steven G. Potkin and Li Shen and Zaven Kachaturian and Richard C. Frank and Peter J. Snyder and Jeffrey A. Kaye and Joseph F. Quinn and Betty Lind and Sara Dolen and Andrzej T. Galecki and Sonia Pawluczyk and Bryan M. Spann and James Brewer and Helen Vanderswag and Judith L. Heidebrink and Joanne L. Lord and Kris A. Johnson and Rachelle Doody and Javier Villanueva-Meyer and Munir Chowdhury and Yaakov Stern and Lawrence Sterling Honig and Karen Lennox Bell and Beau M. Ances and Maria Dreux Carroll and Sue Leon and Mark A. Mintun and Stacy R. Schneider and Daniel C. Marson and Randall Dudley Griffith and David Glenn Clark and Hillel T. Grossman and Effie M. Mitsis and Aliza Romirowsky and Leyla deToledo-Morrell and Raj C. Shah and Ranjan Duara and Daniel J. Varon and Peggy Cochran Roberts and Marilyn S. Albert and Chiadi Onyike and Stephanie A. Kielb and Henry Rusinek and Mony J de Leon and Lidia Glodzik and Susan M De Santi and P. Murali Doraiswamy and Jeffrey R. Petrella and Robert Coleman and Steven E Arnold and Jason H. T. Karlawish and David A. Wolk and Charles D. Smith and Gregory A. Jicha and Randall Griffith and Oscar L. Lopez and MaryAnn Oakley and Donna M. Simpson and Anton P. Porsteinsson and Bonnie S. Goldstein and Kim Martin and Kelly M. Makino and M. Saleem Ismail and Connie Brand and Ruth A. Mulnard and Gaby T. Thai and Catherine Mc-Adams-Ortiz and Kyle Richard Womack and D. T. Mathews and Mary Quiceno and Ramon Diaz-Arrastia and Richard Vern King and Myron Weiner and Kristen Martin-Cook and Michael Devous and Allan I. Levey and James J Lah and Janet S. Cellar and Jeffrey M. Burns and Heather D. S. Anderson and Russell H Swerdlow and Liana G. Apostolova and P. o H Lu and George Bartzokis and Daniel H. S. Silverman and Neill R. Graff-Radford and Francine C. Parfitt and Heather Beth Johnson and Martin R. Farlow and Ann Marie Hake and Brandy R. Matthews and Scott Herring and Christopher H. van Dyck and Richard E. Carson and Martha G Macavoy and Howard Chertkow and Howard Bergman and Chris Hosein and Sandra Elizabeth Black and Bojana Stefanovic and Curtis Caldwell and Ging-Yuek and Robin Hsiung and Howard J Feldman and Benita Mudge and Michele Assaly and Andrew Kertesz and J. Kevin Rogers and Dick Trost and C Bernick and Daniel Silverman and Diana R. Kerwin and M. Marcel Mesulam and Kristina Lipowski and Chuang-Kuo Wu and Nancy Rae Johnson and Carl H. Sadowsky and Walter F. Martinez and Teresa Berdugo Villena and Raymond Scott Turner and Kathleen S. Johnson and Brigid A. Reynolds and Reisa A. Sperling and Keith A. Johnson and Gad A Marshall and Meghan Frey and Jerome A Yesavage and Joy L. Taylor and Barton Lane and Allyson Rosen and Jared Tinklenberg and Marwan N. Sabbagh and Christine Belden and Sandra A. Jacobson and Antonio Felicioli and Ronald J. Killiany and Andrew E. Budson and Alexander Norbash and Patricia Lynn Johnson and Thomas O. Obisesan and Saba Wolday and Salome K Bwayo and Alan M. Lerner and Leon Hudson and Paula J. Ogrocki and Evan Fletcher and O. B. Carmichael and John M. Olichney and Smita D. Kittur and Michael Borrie and T-Y Lee and Rob Bartha and Sterling K. Johnson and Sanjay Asthana and C. M. Gilbert. Carlsson and Adrian Preda and Dana Nguyen and Pierre N. Tariot and Adam S. Fleisher and Stephanie Owen Reeder and Vernice Bates and Horacio A Capote and Michelle M Rainka and Douglas W Scharre and Maria Kataki and Earl A. Zimmerman and Dzintra F Celmins and Alice D. Brown and Godfrey D. Pearlson and Karen L. Blank and Karen Charlotte Anderson and Robert B. Santulli and Eben S. Schwartz and Kaycee M Sink and Jeff D. Williamson and Pankaj Kumar Garg and Franklin S Watkins and Brian R. Ott and Henry Querfurth and Geoffrey N. Tremont and Stephen P. Salloway and P. E. Malloy and Stephen Correia and Howard Jeffrey Rosen and Bruce L. Miller and Jacobo E. Mintzer and Crystal V. Flynn Longmire and Kenneth Spicer and Elizabether Finger and Irina Rachinsky and Dick J. Drost and Connor McCabe and Patricia Ellen Grant and Thomas Michael Ernst and Yoon Hee Chung and Burcu F. Darst and Lexi Pritchett and Ashley Saito and Mishaela DiNino and Bella Eyngorina and Suzanne M. Houston and Lindsay Soderberg and Walter Anton Kaufmann and P C M van Zijl and Hilda Rizzo-Busack and Mohsin Javid and Natasha N. Mehta and Erika J. Ruberry and Alisa Powers and Bruce R. Rosen and Nitzah Gebhard and Holly Manigan and Jean A. Frazier and Lauren J. Yakutis and Michael Lewis Hill and Joan Bosson-Heenan and Heatherly Carlson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 10},
  pages={
          3985-90
        }
}
Visual cortical surface area varies two- to threefold between human individuals, is highly heritable, and has been correlated with visual acuity and visual perception. However, it is still largely unknown what specific genetic and environmental factors contribute to normal variation in the area of visual cortex. To identify SNPs associated with the proportional surface area of visual cortex, we performed a genome-wide association study followed by replication in two independent cohorts. We… CONTINUE READING

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