Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia

@article{RodrguezSantiago2010AssociationOC,
  title={Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia},
  author={Benjam{\'i}n Rodr{\'i}guez-Santiago and Anna Brunet and Beatriz Sobrino and Clara Serra-Juh{\'e} and Raquel Flores and Ll Armengol and Elisabet Vilella and Elisabeth Gabau and M{\'i}riam Guitart and Roser Guillamat and L Martorell and Joaqu{\'i}n Valero and Alfonso Guti{\'e}rrez-Zotes and Antonio Labad and Arkaitz Carracedo and Xavier Estivill and Luis A. P{\'e}rez-Jurado},
  journal={Molecular Psychiatry},
  year={2010},
  volume={15},
  pages={1023-1033}
}
Copy number variants (CNVs) are a substantial source of human genetic diversity, influencing the variable susceptibility to multifactorial disorders. Schizophrenia is a complex illness thought to be caused by a number of genetic and environmental effects, few of which have been clearly defined. Recent reports have found several low prevalent CNVs associated with the disease. We have used a multiplex ligation-dependent probe amplification-based (MLPA) method to target 140 previously reported and… CONTINUE READING
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