Association of common SNP rs1136410 in PARP1 gene with the susceptibility to male infertility with oligospermia

@article{Chen2014AssociationOC,
  title={Association of common SNP rs1136410 in PARP1 gene with the susceptibility to male infertility with oligospermia},
  author={Hui Chen and Xiao-Ying Pu and Ruo-peng Zhang and A Zhou-cun},
  journal={Journal of Assisted Reproduction and Genetics},
  year={2014},
  volume={31},
  pages={1391-1395}
}
This study aims to explore possible associations between polymorphisms of common SNP rs1136410 and rS1805405 in PARP1 gene and male infertility with spermatogenesis impairment. The polymorphic distributions of SNP rs1136410 and rS1805405 were investigated by polymerase chain reaction and restriction fragment length polymorphism analysis in a Chinese cohort including 371 infertile patients with idiopathic azoospermia or oligospermia and 231 controls. Significant differences in the frequencies of… CONTINUE READING
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