Association of common C-reactive protein (CRP) gene polymorphisms with baseline plasma CRP levels and fenofibrate response: the GOLDN study.

@article{Shen2008AssociationOC,
  title={Association of common C-reactive protein (CRP) gene polymorphisms with baseline plasma CRP levels and fenofibrate response: the GOLDN study.},
  author={Jian Shen and Donna K Arnett and Laurence D. Parnell and James M. Peacock and Chao-Qiang Lai and James E. Hixson and Michael Y Tsai and Michael A. Province and Robert J. Straka and Jos{\'e} M. Ordov{\'a}s},
  journal={Diabetes care},
  year={2008},
  volume={31 5},
  pages={910-5}
}
OBJECTIVE C-reactive protein (CRP) is an inflammatory marker that contributes to the prediction of cardiovascular disease. We investigated the influences of CRP polymorphisms on baseline CRP levels and fenofibrate-induced CRP changes in subjects with the metabolic syndrome. RESEARCH DESIGN AND METHODS We examined the association of CRP single nucleotide polymorphisms (SNPs) (m772A>G, m301G>A >T, i178T>A, 3u1273C>T, and 3u2131C>T) with baseline plasma CRP levels among 1,123 white U.S… CONTINUE READING
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