Association of collagen type I alpha 1 gene polymorphism with inguinal hernia

@article{Sezer2013AssociationOC,
  title={Association of collagen type I alpha 1 gene polymorphism with inguinal hernia},
  author={Saime Sezer and N. Şimşek and Havva Tuğba Çelik and Gonul Erden and Gokhan Tuna Ozturk and Arife Polat D{\"u}zg{\"u}n and Faruk Coşkun and Kadir Aras Demircan},
  journal={Hernia},
  year={2013},
  volume={18},
  pages={507-512}
}
AbstractPurpose A positive family history is an important risk factor for inguinal hernia development, suggesting a genetic trait for hernia disease. However, gene mutations responsible for abdominal wall hernia formation in humans have not yet been studied. We aimed to evaluate whether the functional Sp1 binding site polymorphism within intron 1 of the collagen type I, alpha 1 (COL1A1) gene was associated specifically with inguinal hernia disease.Methods85 participants with surgically… Expand
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