Association of codon 10 polymorphism of the transforming growth factor beta 1 gene with prostate cancer and hyperplasia in an Iranian population.

@article{Omrani2009AssociationOC,
  title={Association of codon 10 polymorphism of the transforming growth factor beta 1 gene with prostate cancer and hyperplasia in an Iranian population.},
  author={Mir Davood Omrani and Soroush Taghipour-Bazargani and Shaker Salari-Lak and Morteza Bagheri},
  journal={Urologia internationalis},
  year={2009},
  volume={83 3},
  pages={329-32}
}
INTRODUCTION Genetic polymorphisms in codons 10 of the transforming growth factor beta(1) (TGF-beta(1)) gene TGFB1 have been shown to be associated with the production of high or low TGF-beta(1) levels. The role of this polymorphism in the development of prostate cancer and hyperplasia was investigated. SUBJECTS AND METHODS Using the allele-specific oligonucleotide polymerase chain reaction method, the association between the polymorphism at codon 10 of the TGFB1 gene and the risk of prostate… CONTINUE READING

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