Association of co-stimulatory human B-lymphocyte antigen B7-2 (CD86) gene polymorphism with colorectal cancer risk

@inproceedings{Azimzadeh2013AssociationOC,
  title={Association of co-stimulatory human B-lymphocyte antigen B7-2 (CD86) gene polymorphism with colorectal cancer risk},
  author={Pedram Azimzadeh and S Romani and Hanieh Mirtalebi and S Mohammad Reza Fatemi and Shabnam Kazemian and Mahsa Khanyaghma and Seyed Reza Mohebbi},
  booktitle={Gastroenterology and hepatology from bed to bench},
  year={2013}
}
AIM This study investigated the role of CD86 +237 G/C polymorphism in intensifying the risk of CRC development. BACKGROUND Colorectal cancer (CRC) is a multi-factorial diseases. Genetic background could affect the susceptibility of individuals to CRC development. CD86 is a co-stimulatory factor on antigen-presenting cells that plays key roles in several cancer related mechanisms such as autoimmunity, transplantation and tumor immunity. PATIENTS AND METHODS A total of 300 individuals, 150… CONTINUE READING

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Interleukin-16 (IL-16) gene polymorphisms in Iranian patients with colorectal cancer.

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