Association of circulating TNF-alpha and IL-6 with ageing and parkinsonism.


INTRODUCTION We propose that the increase in TNF-alpha and IL-6 in the brain in idiopathic parkinsonism is in response to a peripheral immune/ inflammatory process, so ubiquitous as to be responsible for the resemblance between ageing and parkinsonism. METHODS Circulating cytokine was measured in 78 subjects with idiopathic parkinsonism and 140 without… (More)


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