Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes.

@article{Pallier2003AssociationOC,
  title={Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes.},
  author={Coralie Pallier and Paola Scaffidi and St{\'e}phanie Chopineau-Proust and Alessandra Agresti and Patrice L. Nordmann and Marco Emilio Bianchi and Vincent Mar{\'e}chal},
  journal={Molecular biology of the cell},
  year={2003},
  volume={14 8},
  pages={
          3414-26
        }
}
High mobility group box (HMGB) 1 and 2 are two abundant nonhistone nuclear proteins that have been found in association with chromatin. Previous studies based on immunofluorescence analysis indicated that HMGB1 dissociates from chromosomes during mitosis. In the present work, HMGB1 and 2 subcellular localization was reinvestigated in living cells by using enhanced green fluorescent protein- and Discosome sp. red fluorescent protein-tagged proteins. Contrary to previous reports, HMGB1 and 2 were… CONTINUE READING
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