Association of childhood trauma exposure and GABRA2 polymorphisms with risk of posttraumatic stress disorder in adults

@article{Nelson2009AssociationOC,
  title={Association of childhood trauma exposure and GABRA2 polymorphisms with risk of posttraumatic stress disorder in adults},
  author={Elliot C. Nelson and Arpana Agrawal and Michele L. Pergadia and Michael T Lynskey and Alexandre A. Todorov and Jen Chyong Wang and R. D. Todd and Nicholas G. Martin and A Christopher Heath and Alison M. Goate and Grant W. Montgomery and Pamela A. F. Madden},
  journal={Molecular Psychiatry},
  year={2009},
  volume={14},
  pages={234-235}
}
Individuals who experience child abuse are at increased risk for developing posttraumatic stress disorder (PTSD) as a direct result of the abuse and upon exposure to subsequent trauma. A recent examination of PTSD symptoms in adults found evidence for a significant G E interaction involving a quantitative measure of child abuse exposure and four single-nucleotide polymorphisms (SNPs) of FKBP5 including two SNPs for which an association of the same alleles with peritraumatic dissociative… CONTINUE READING

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Supplementary Information accompanies the paper on the Molecular Psychiatry website (http://www.nature.com/mp) Letters to the Editor

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