Association of cephalic neural crest cells with cardiovascular development, particularly that of the semilunar valves

  title={Association of cephalic neural crest cells with cardiovascular development, particularly that of the semilunar valves},
  author={Kazushi Takamura and Takahiro Okishima and Shozo Ohdo and Kunio Hayakawa},
  journal={Anatomy and Embryology},
SummaryThe quail-chick chimera method was used to examine whether neural crest cells were associated with the formation of semilunar valves. From the metencephalon to somite 5, or from the otocyst to somite 3, left, right, or bilateral neural folds, including the neural crest, were transplanted. Among embryos used for the experiment, three into which left neural crest cells were transplanted, two into which right neural crest cells were transplanted, and two into which bilateral neural crest… 

Participation of Neural Crest Cells in Cardiovascular Morphogenesis of Chick Embryos

New experimental findings are reported and the relationship between neural crest cells and congenital malformation syndromes, especially the DiGeorge sequence is reviewed.

Formation of cartilage in the heart of the Spanish terrapin, Mauremys leprosa (Reptilia, Chelonia)

The findings are consistent with the assumption that the precursors of the cardiac chondrocytes in chelonians are neural crest‐derived cells of nonmuscular nature, and point to the possibility that cells from the neural crest populate the embryonic pars fibrosa of the horizontal septum, thereby contributing to its alignment with the aorticopulmonary septums.

The Role of Cell Tracing and Fate Mapping Experiments in Cardiac Outflow Tract Development, New Opportunities through Emerging Technologies

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Role of Epigenetics in Cardiac Development and Congenital Diseases.

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Analysis of cranial neural crest distribution in the developing heart using quail-chick chimeras.

Information indicates that ablations of neural crest presumptive for arches 3, 4, and 6 influence heart development directly while lesions of other areas of cranial neural crest probably influenceHeart development only secondarily with the primary effects occurring in the pharyngeal arches.

Nodose placode provides ectomesenchyme to the developing chick heart in the absence of cardiac neural crest

  • M. Kirby
  • Biology, Medicine
    Cell and Tissue Research
  • 2004
Although placode-derived ectomesenchyme helps to strengthen the wall of the cardiac outflow vessel, it is not competent to induce conotruncal and aorticopulmonary septal closure.

Distribution of the neural crest cells in the heart of birds: a three dimensional analysis

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Neural crest cells contribute to normal aorticopulmonary septation.

By analyzing the hearts of quail-chick chimeras, it was found that neural crest cells at the level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum, resulting in common arterial outflow channels or transposition of the great vessels.

Characterization of conotruncal malformations following ablation of “cardiac” neural crest

The present study defined more precisely the regions of premigratory cranial neural crest which are needed for normal conotruncal development and ablated various regions and lengths using microcautery.

Distribution of fibronectin during the morphogenesis of the truncus

  • J. Icardo
  • Biology, Medicine
    Anatomy and Embryology
  • 2004
The close association between the fluorescence and the surface of the cells involved in formation of the aorto-pulmonary septum and the arterial tunica media suggests that fibronectin may be implicated in the formation of both structures.

Development of the chick heart