Association of candidate genetic variants with restless legs syndrome in end stage renal disease: a multicenter case-control study in Taiwan.

@article{Lin2014AssociationOC,
  title={Association of candidate genetic variants with restless legs syndrome in end stage renal disease: a multicenter case-control study in Taiwan.},
  author={C. H. Lin and Mei Ling Chen and Victor K. C. Wu and Wan Yi Li and Hiu Ngar Sy and Shu Lin Wu and Choong Chor Chang and Peter Ka Fung Chiu and Horng Huei Liou and Chien Yu Lin and Hyuk Won Chang and Shiyng Yu Lin and Kwan Dun Wu and Yue Ming Chen and R. M. Wu},
  journal={European journal of neurology},
  year={2014},
  volume={21 3},
  pages={492-8}
}
BACKGROUND AND PURPOSE Recent genome-wide association studies have shown associations between multiple genetic variants and primary restless legs syndrome (RLS). Their roles in end stage renal disease (ESRD) related secondary RLS are not clear and studies in Asian populations are scarce. The association between candidate genetic variants and uremic RLS was investigated in a large cohort of Taiwanese dialysis patients. METHODS Sixteen RLS-related genetic variants at six loci, including MEIS1… CONTINUE READING