Association of arthritis with a gene complex encoding C-type lectin-like receptors.

  title={Association of arthritis with a gene complex encoding C-type lectin-like receptors.},
  author={Johnny C. Lorentzen and Line Mari Flornes and Carina Ekl{\"o}w and Liselotte B{\"a}ckdahl and Ulrica Ribbhammar and Jian Ping Guo and Marina V. Smolnikova and Erik Dissen and Maria Seddighzadeh and Anthony J. Brookes and Lars Alfredsson and Lars Klareskog and Leonid Padyukov and Sigbj{\"o}rn Fossum},
  journal={Arthritis and rheumatism},
  volume={56 8},
OBJECTIVE To identify susceptibility genes in a rat model of rheumatoid arthritis (RA) and to determine whether the corresponding human genes are associated with RA. METHODS Genes influencing oil-induced arthritis (OIA) were position mapped by comparing the susceptibility of inbred DA rats with that of DA rats carrying alleles derived from the arthritis-resistant PVG strain in chromosomal fragments overlapping the quantitative trait locus Oia2. Sequencing of gene complementary DNA (cDNA) and… CONTINUE READING


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