Association of an activator with an RNA polymerase II holoenzyme.

  title={Association of an activator with an RNA polymerase II holoenzyme.},
  author={Christoph J Hengartner and Craig Marshall Thompson and Jianhua Zhang and David M. Chao and Sha Mei Liao and Anthony J Koleske and Shoji Okamura and Richard A. Young},
  journal={Genes & development},
  volume={9 8},
RNA polymerase II holoenzymes have been described that consist of RNA polymerase II, a subset of general transcription factors, and four SRB proteins. The SRB proteins, which were identified through a selection for genes involved in transcription initiation by RNA polymerase II in vivo, are a hallmark of the holoenzyme. We report here the isolation and characterization of additional SRB genes. We show that the products of all nine SRB genes identified thus far are components of the RNA… CONTINUE READING
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