Association of an MDR1 gene (C3435T) polymorphism with acute leukemia in India.

Abstract

The multidrug resistance (MDR1) gene product P-glycoprotein is a membrane bound protein that functions as an ATP-dependent efflux pump, transporting exogenous and endogenous substrates from the cells. Since it plays an important role in chemotherapy, there is an increasing interest in the possible significance of genetic variation in MDR1. Our main… (More)

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@article{Rao2010AssociationOA, title={Association of an MDR1 gene (C3435T) polymorphism with acute leukemia in India.}, author={D. Nageswara Rao and Chetukuri Anuradha and S. Vishnupriya and Kesiraju Sailaja and Dr. Surekha and Digumarti Raghunadharao and Senthil Jagannathan Rajappa}, journal={Asian Pacific journal of cancer prevention : APJCP}, year={2010}, volume={11 4}, pages={1063-6} }