Association of allergic contact dermatitis with a promoter polymorphism in the IL16 gene.

@article{Reich2003AssociationOA,
  title={Association of allergic contact dermatitis with a promoter polymorphism in the IL16 gene.},
  author={K Reich and G{\"o}tz Alexander Westphal and Inke R. K{\"o}nig and R M{\"o}ssner and Ullrich Krueger and Andreas Ziegler and Christine Neumann and Axel Schnuch},
  journal={The Journal of allergy and clinical immunology},
  year={2003},
  volume={112 6},
  pages={1191-4}
}
BACKGROUND There is evidence that IL-16, a cytokine that induces chemotactic responses in CD4(+) T cells, eosinophils, and dendritic cells, plays an important role during different types of cutaneous inflammatory responses, including allergic contact dermatitis (ACD) and atopic dermatitis (AD). OBJECTIVES We sought to test for association between a promoter polymorphism in the IL16 gene (T to C transition at position -295) and ACD and AD, respectively. METHODS IL16 -295 genotypes were… CONTINUE READING
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