Association of adiponectin multimers with Barrett's oesophagus.

  title={Association of adiponectin multimers with Barrett's oesophagus.},
  author={Joel H. Rubenstein and John Y Kao and Ryan D. Madanick and Meng Zhang and Meilin Wang and Melissa B. Spacek and Jennifer L. Donovan and Stephanie D Bright and N J Shaheen},
  volume={58 12},
OBJECTIVE Barrett's oesophagus is associated with abdominal obesity. Adiponectin is a peptide that is secreted from adipocytes and circulates in three multimeric forms: low molecular weight (LMW), middle molecular weight (MMW), and high molecular weight (HMW). The anti-inflammatory effects of adiponectin are specific to individual multimers, with LMW being most anti-inflammatory. We postulated that circulating levels of adiponectin and its multimers would be associated with the risk of Barrett… CONTINUE READING
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