Association of adiponectin and resistin with adipose tissue compartments, insulin resistance and dyslipidaemia

@article{Farvid2005AssociationOA,
  title={Association of adiponectin and resistin with adipose tissue compartments, insulin resistance and dyslipidaemia},
  author={Maryam S. Farvid and Theodore W. K. Ng and Dick C. Chan and P. Hugh R. Barrett and Gerald F. Watts},
  journal={Diabetes},
  year={2005},
  volume={7}
}
Aim:  In this study, we investigated the association of plasma adiponectin and resistin concentrations with adipose tissue compartments in 41 free‐living men with a wide range of body mass index (22–35 kg/m2). 
Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids.
TLDR
For a given level of truncal fat mass, a large lower body fat mass is associated with an advantageous blood lipid profile, which may be partially mediated by the relationships to both insulin sensitivity and serum adiponectin level.
[The levels of resistin and other adipokines in patients with hypothyroidism].
TLDR
The patients with hypothyroidism were found to have statistically significantly enhanced insulin resistance (IR) and compensatory hyperinsulinemia in the presence of android fat distribution and there was a correlation of leptin and adiponectin with fat metabolic parameters.
Subcutaneous rather than visceral adipose tissue is associated with adiponectin levels and insulin resistance in young men.
TLDR
SAT rather than VAT was inversely associated with adiponectin levels, and, interestingly, fat on the lower extremities was positively associated with obesity, in a population-based study on relatively healthy young men.
Association of adiponectin, resistin and high sensitive CRP level with the metabolic syndrome in childhood and adolescence.
  • F. Çizmecioğlu, N. Etiler, +5 authors Ş. Hatun
  • Medicine
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
  • 2009
TLDR
It is concluded that the best marker for MS diagnosis is the measurement of waist circumference, which had the highest sensitivity and specificity for predicting MS in ROC analysis.
Plasma resistin levels correlate with determinants of the metabolic syndrome.
TLDR
Plasma resistin levels are increased in presence of the metabolic syndrome and are associated with increased cardiovascular risk.
Circulating adiponectin represents a biomarker of the association between adiposity and bone mineral density
TLDR
In conclusion, adiponectin may represent a biomarker in the relationship between visceral fat mass and BMD, however, this association is probably confounded by the specific body composition parameters in postmenopausal women.
Impact of Ghrelin and Adiponectin on Metabolic and Cardiovascular Effects
TLDR
Ghrelin has a crucial role in the regulation of food intake and energy homeostasis, and adiponectin is secreted by adipocytes, and it has been proposed to mediate obesity-related insulin resistance.
Relatively high levels of serum adiponectin in obese women, a potential indicator of anti-inflammatory dysfunction: Relation to sex hormone-binding globulin
TLDR
Relationship between excess adiposity and adiponectin levels is inconsistent in Turkish adults and discloses significant relationship with inflammatory markers and HDL only in men, not in women in whom it is influenced by SHBG, with consequent attenuation of its anti-inflammatory activities.
Increased insulin sensitivity in patients with anorexia nervosa: the role of adipocytokines.
TLDR
It is demonstrated that anorexia nervosa is associated with significantly decreased plasma leptin and resistin levels, markedly increased plasma adiponectin levels and increased insulin sensitivity.
Association of Circulating Resistin with Metabolic Risk Factors in Indian Females Having Metabolic Syndrome
TLDR
A positive correlation between resistin and factors of MetS except high-density lipoprotein which was found to be negatively correlated in Indian female subjects is demonstrated.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 38 REFERENCES
Plasma adiponectin in overweight, nondiabetic individuals with or without insulin resistance
TLDR
This cross‐sectional study investigated the relationship between plasma adiponectin and a range of anthropometric, glycaemic, lipid and inflammatory parameters in overweight and obese subjects expressing characteristics of the metabolic syndrome.
Plasma resistin, adiponectin and leptin levels in lean and obese subjects: correlations with insulin resistance.
TLDR
In this small group of patients, it was demonstrated that insulin resistance correlated most strongly with leptin levels and a significant correlation between resistin levels and insulin resistance was also observed.
Regional differences and effect of weight reduction on human fat cell metabolism
TLDR
The effect of submaximal concentrations of insulin on glucose incorporation increased with weight reduction implying increased cellular insulin sensitivity, and the metabolism of adipocytes from severely obese patients was investigated.
Resistin: an adipocyte‐derived hormone. Has it a role in diabetes and obesity?
TLDR
The purpose of this review is to summarize the experimental findings to date and to discuss the extent to which the original hypotheses relating to resistin have been confirmed or questioned.
Correlation between serum resistin level and adiposity in obese individuals.
TLDR
Resistin appears to be related to human adiposity and to be a possible candidate factor in human insulin resistance.
Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans.
TLDR
The inverse relationship between plasma adip onectin and cytokines in vivo and the cytokine-induced reduction in adiponectin mRNA in vitro suggests that endogenous cytokines may inhibit adiponECTin.
Reduction in visceral adipose tissue is associated with improvement in apolipoprotein B-100 metabolism in obese men.
TLDR
The hypothesis that a reduction in visceral adipose tissue is associated with a decrease in the hepatic secretion of VLDL apoB, and this may be due to a decreases in portal lipid substrate supply is supported.
Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex
TLDR
It is suggested that adiponectin concentrations are determined by intra-abdominal fat mass, with additional independent effects of age and sex, and could link intra- abdominalFat with insulin resistance and an atherogenic lipoprotein profile.
Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects.
TLDR
Cross-sectional studies in middle-aged women and healthy young subjects found that serum resistin levels did not correlate with markers of adiposity, including body mass index, waist-to-hip ratio, or fat mass, or insulin resistance assessed by homeostasis model, lipid profile, or serum leptin levels; but females had higherresistin levels than males.
Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism.
TLDR
In nondiabetic individuals, high adiponectin predicts increased insulin sensitivity, independent of low body fat mass and affects not only insulin-stimulated glucose disposal but also lipoprotein metabolism and insulin-mediated suppression of postprandial FFA release.
...
1
2
3
4
...