Association of acetaminophen hepatotoxicity with fasting and ethanol use.

@article{Whitcomb1994AssociationOA,
  title={Association of acetaminophen hepatotoxicity with fasting and ethanol use.},
  author={D. Whitcomb and G. D. Block},
  journal={JAMA},
  year={1994},
  volume={272 23},
  pages={
          1845-50
        }
}
OBJECTIVES To evaluate the association of fasting and alcohol use with hepatotoxicity from acetaminophen ingested for therapeutic reasons. DESIGN Retrospective case series. SETTING Hospitals of the University of Pittsburgh (Pa) Medical Center. PATIENTS A total of 126,779 discharge summaries from January 1987 to July 1993 were reviewed using a comprehensive, whole-text-indexed medical database to identify all patients with acetaminophen ingestion and hepatotoxicity. These patients were… Expand
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