Association of a variant in the CHRNA5-A3-B4 gene cluster region to heavy smoking in the Italian population

@article{Sorice2011AssociationOA,
  title={Association of a variant in the CHRNA5-A3-B4 gene cluster region to heavy smoking in the Italian population},
  author={Rossella Sorice and Silvia Bione and Serena Sansanelli and Sheila Ulivi and Emmanouil Athanasakis and Carmela Lanzara and Teresa Nutile and Cinzia Sala and Clara Camaschella and Pio d'Adamo and Paolo Gasparini and Marina Ciullo and Daniela Toniolo},
  journal={European Journal of Human Genetics},
  year={2011},
  volume={19},
  pages={593-596}
}
Large-scale population studies have established that genetic factors contribute to individual differences in smoking behavior. Linkage and genome-wide association studies have shown many chromosomal regions and genes associated with different smoking behaviors. One study was the association of single-nucleotide polymorphisms (SNPs) in the CHRNA5-A3-B4 gene cluster to nicotine addiction. Here, we report a replication of this association in the Italian population represented by three genetically… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 19 references

Genome - wide association study of smoking initiation and current smoking

  • JM Vink, AB Smit, de Geus EJC
  • Am J Hum Genet
  • 2009

A candidate gene approach identifies the CHRNA 5 - A 3 - B 4 region as a risk factor for agedependent nicotine addiction

  • RB Weiss, TB Baker, DS Cannon
  • PLoSGenet
  • 2008

Similar Papers

Loading similar papers…