Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence

@article{Nakamura1999AssociationOA,
  title={Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence},
  author={Takako Nakamura and Sachio Matsushita and Naoki Nishiguchi and Minoru Kimura and Atsunori Yoshino and Susumu Higuchi},
  journal={Molecular Psychiatry},
  year={1999},
  volume={4},
  pages={85-88}
}
Approximately 10% of Japanese alcoholics develop their disease despite having an inactive form of aldehyde dehydrogenase-2 (ALDH2),1 known as a genetic deterrent of heavy drinking due to adverse reactions after drinking.2 Such alcoholics are considered to be advantageous in genetic research because they should show reduced heterogeneity and possess genetic factors conferring susceptibility to alcohol dependence. Examination of the −1438 A/G polymorphism of the serotonin 2A (5HT2A) receptor gene… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Similar Papers

Loading similar papers…