Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction.

@article{Togsverd2008AssociationOA,
  title={Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction.},
  author={Mads Togsverd and Thomas M Werge and L{\'a}szl{\'o} B. Tank{\'o} and Yu Zhao Bagger and Thomas J Hansen and Gerong Qin and Claus Christiansen and Henrik Berg Rasmussen},
  journal={Journal of affective disorders},
  year={2008},
  volume={106 1-2},
  pages={169-72}
}
BACKGROUND Depression has a multifactorial etiology which involves genetic factors and comorbid diseases. METHODS A cross-sectional sample of 1371 elderly women (mean age=69.2 years) was examined. Detailed information on their health was obtained. Cognitive functions were assessed by the Short Blessed Test and the Animal Naming Task. A 19 bp insertion/deletion polymorphism in the dopamine beta-hydroxylase (DBH) gene, the apolipoprotein (APOE) epsilon2/epsilon3/epsilon4 variation and 5-HTTLPR… CONTINUE READING

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