Association of a common vitamin D-binding protein polymorphism with inflammatory bowel disease.

@article{Eloranta2011AssociationOA,
  title={Association of a common vitamin D-binding protein polymorphism with inflammatory bowel disease.},
  author={Jyrki J. Eloranta and Christa Wenger and Jessica Mwinyi and Christian Hiller and Christoph Gubler and Stephan R. Vavricka and Michael A. H. Fried and Gerd A Kullak-Ublick},
  journal={Pharmacogenetics and genomics},
  year={2011},
  volume={21 9},
  pages={559-64}
}
OBJECTIVE Inflammatory bowel diseases (IBDs), Crohn's disease, and ulcerative colitis (UC), are multifactorial disorders, characterized by chronic inflammation of the intestine. A number of genetic components have been proposed to contribute to IBD pathogenesis. In this case-control study, we investigated the association between two common vitamin D-binding protein (DBP) genetic variants and IBD susceptibility. These two single nucleotide polymorphisms (SNPs) in exon 11 of the DBP gene, at… CONTINUE READING