Association of a New Type of Cytopathogenic Myxovirus with Infantile Croup

@article{Chanock1956AssociationOA,
  title={Association of a New Type of Cytopathogenic Myxovirus with Infantile Croup},
  author={Robert M. Chanock},
  journal={The Journal of Experimental Medicine},
  year={1956},
  volume={104},
  pages={555 - 576}
}
Viruses producing an unusual "sponge-like" cytopathogenic change in monkey kidney tissue culture were isolated from the pharyngeal swabs of 2 of 12 infants with croup. The infants from whom the viruses were isolated and 3 additional patients developed significant increases in neutralizing or hemagglutination-inhibition and complement-fixing or all 3 varieties of antibody during convalescence. The isolated agents appeared to be similar antigenically. Fluid from infected monkey kidney tissue… CONTINUE READING