Association of Vpu with hepatitis C virus NS3/4A stimulates transcription of type 1 human immunodeficiency virus.

@article{Kang2012AssociationOV,
  title={Association of Vpu with hepatitis C virus NS3/4A stimulates transcription of type 1 human immunodeficiency virus.},
  author={Lei Kang and Zhen Luo and Youxing Li and Wenjing Zhang and Wei Sun and Wei Li and Yanni Chen and Fang Liu and Xueshan Xia and Ying Zhu and Jianguo Wu},
  journal={Virus research},
  year={2012},
  volume={163 1},
  pages={74-81}
}
Type 1 human immunodeficiency virus (HIV-1) and hepatitis C virus (HCV) are deadly bloodborne-transmitting pathogens. Due to sharing the routes of transmission, co-infection of HIV-1 and HCV is common with a high rate. Co-infection of HCV affects morbidity and mortality of patients with AIDS and impairs their tolerance to antiretroviral therapy. In this study, the roles of HCV proteins in the regulation of HIV-1 replication and the molecular mechanism involved in such regulation were… CONTINUE READING