Association of Vitamin D Receptor Polymorphisms With the Risk of Nonmelanoma Skin Cancer in Adults.

@article{Burns2017AssociationOV,
  title={Association of Vitamin D Receptor Polymorphisms With the Risk of Nonmelanoma Skin Cancer in Adults.},
  author={Elaine Burns and Purushotham Guroji and Israr Ahmad and Hana M. Nasr and Yingxue Wang and Iman A Tamimi and Elijah Stiefel and Mohammad S. Abdelgawwad and Abdullah Shaheen and Anum Fatima Muzaffar and Lisa M Bush and Christina B Hurst and Russell Lee Griffin and Craig A. Elmets and Nabiha Yusuf},
  journal={JAMA dermatology},
  year={2017}
}
Importance Protective effects of UV-B radiation against nonmelanoma skin cancer (NMSC) are exerted via signaling mechanisms involving the vitamin D receptor (VDR). Recent studies have examined single-nucleotide polymorphisms (SNPs) in the VDR, resulting in contradictory findings as to whether these polymorphisms increase a person's risk for NMSC. Objective To examine whether the polymorphisms in the VDR gene are associated with the development of NMSC and the demographic characteristics of… CONTINUE READING
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