Association of Vascular endothelial growth factor +405G>C 5’-untranslated region polymorphism and Plasma VEGF levels in Breast cancer patients


Objective: Angiogenesis is necessary for tumor growth, invasion, and metastasis. A key mediator in neoangiogenesis is vascular endothelial growth factor (VEGF). DNA sequence variations in the VEGF gene may lead to altered VEGFexpression and/or activity, thereby causing interindividual differences in the susceptibility to breast cancer via their actions on… (More)


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