Association of VEGF and eNOS gene polymorphisms in type 2 diabetic retinopathy.

@article{Suganthalakshmi2006AssociationOV,
  title={Association of VEGF and eNOS gene polymorphisms in type 2 diabetic retinopathy.},
  author={Balasubbu Suganthalakshmi and Rajendran Anand and Ramasamy Kim and R. Devi Mahalakshmi and Sundaramoorthi Karthikprakash and Perumalsamy Namperumalsamy and Periasamy Sundaresan},
  journal={Molecular vision},
  year={2006},
  volume={12},
  pages={336-41}
}
PURPOSE Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis, and nitric oxide (NO) is an upstream and downstream regulator of VEGF mediated angiogenesis. VEGF and NO have been suggested to play an important role in the pathogenesis of microvascular complications in diabetic retinopathy (DR). The objective of this study was to examine the genetic variations of the VEGF and eNOS gene and assess their possible relationship to DR in type 2 diabetic patients in the Indian… CONTINUE READING

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