Association of Thalamic Dysconnectivity and Conversion to Psychosis in Youth and Young Adults at Elevated Clinical Risk.

@article{Anticevic2015AssociationOT,
  title={Association of Thalamic Dysconnectivity and Conversion to Psychosis in Youth and Young Adults at Elevated Clinical Risk.},
  author={Alan Anticevic and Kristen M. Haut and John D Murray and Grega Repov{\vs} and Genevieve J. Yang and Caroline Diehl and Sarah C. McEwen and Carrie E. Bearden and Jean Addington and Bradley G. Goodyear and Kristin S. Cadenhead and Heline Mirzakhanian and Barbara A. Cornblatt and Doreen M. Olvet and Daniel H. Mathalon and Thomas H. McGlashan and Diana O. Perkins and Aysenil Belger and Larry J. Seidman and Ming T. Tsuang and Theo G M van Erp and Elaine F. Walker and Stephan Hamann and Scott W. Woods and MaoLin Qiu and Tyrone D. Cannon},
  journal={JAMA psychiatry},
  year={2015},
  volume={72 9},
  pages={882-91}
}
IMPORTANCE Severe neuropsychiatric conditions, such as schizophrenia, affect distributed neural computations. One candidate system profoundly altered in chronic schizophrenia involves the thalamocortical networks. It is widely acknowledged that schizophrenia is a neurodevelopmental disorder that likely affects the brain before onset of clinical symptoms. However, no investigation has tested whether thalamocortical connectivity is altered in individuals at risk for psychosis or whether this… CONTINUE READING

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