Association of TERT Promoter Mutation, But Not BRAF Mutation, With Increased Mortality in PTC.

@article{George2015AssociationOT,
  title={Association of TERT Promoter Mutation, But Not BRAF Mutation, With Increased Mortality in PTC.},
  author={Jonathan R. George and Ying C. Henderson and Michelle D Williams and Dianna B. Roberts and Hu Hei and Stephen Y Lai and Gary L Clayman},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2015},
  volume={100 12},
  pages={E1550-9}
}
CONTEXT Papillary thyroid carcinoma (PTC) carrying the BRAF mutation has been reported to be associated with high recurrence and potentially increased mortality. PTC carrying the TERT promoter mutation has been associated with older age, recurrence, and aggressive disease. OBJECTIVE The objective of this study was to determine the association of BRAF and TERT promoter gene alterations with recurrence and survival in a high-risk population. DESIGN Genomic DNA was analyzed for the BRAF… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…