Association of SENPs single-nucleotide polymorphism and breast cancer in Chinese population

@article{Cai2019AssociationOS,
  title={Association of SENPs single-nucleotide polymorphism and breast cancer in Chinese population},
  author={Jiaqin Cai and Xiaoxia Wei and G. Zhang and Yuxia Sui and J. Zhuang and Zhenhua Liu and H. Sun},
  journal={Medicine},
  year={2019},
  volume={98}
}
  • Jiaqin Cai, Xiaoxia Wei, +4 authors H. Sun
  • Published 2019
  • Medicine
  • Medicine
  • Abstract SUMO-specific Cysteine Proteases (SENPs) have involvement in the initiation and progression of human cancers. In the present study, we evaluated the association of SENPs polymorphism with susceptibility as well as clinicopathologic features and patients’ response of breast cancer (BC) in a Chinese population. We genotyped SENP1 (rs61918808), SENP2 (rs6762208), SENP7 (rs61697963) by sequencing in a case–control study including 210 BC patients and 225 healthy volunteers. Odds ratios (ORs… CONTINUE READING

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