Association of RIG-I with innate immunity of ducks to influenza.

@article{Barber2010AssociationOR,
  title={Association of RIG-I with innate immunity of ducks to influenza.},
  author={Megan R.W. Barber and Jerry R. Aldridge and Robert G Webster and Katharine E Magor},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 13},
  pages={
          5913-8
        }
}
Ducks and wild waterfowl perpetuate all strains of influenza viruses in nature. In their natural host, influenza viruses typically cause asymptomatic infection and little pathology. Ducks are often resistant to influenza viruses capable of killing chickens. Here, we show that the influenza virus sensor, RIG-I, is present in ducks and plays a role in clearing an influenza infection. We show evidence suggesting that RIG-I may be absent in chickens, providing a plausible explanation for their… CONTINUE READING

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