Association of Preoperative and Postoperative Serum Carcinoembryonic Antigen and Colon Cancer Outcome.

@article{Konishi2018AssociationOP,
  title={Association of Preoperative and Postoperative Serum Carcinoembryonic Antigen and Colon Cancer Outcome.},
  author={Tsuyoshi Konishi and Yoshifumi Shimada and Meier Hsu and Lauren Tufts and Rosa Jim{\'e}nez-Rodr{\'i}guez and Andrea Cercek and Rona D Yaeger and Leonard Saltz and Jason J. Smith and Garrett M. Nash and Jos{\'e} G. Guillem and Philip B. Paty and Julio E Garcia-Aguilar and Mithat Gonen and Martin R Weiser},
  journal={JAMA oncology},
  year={2018},
  volume={4 3},
  pages={309-315}
}
Importance Guidelines recommend measuring preoperative carcinoembryonic antigen (CEA) in patients with colon cancer. Although persistently elevated CEA after surgery has been associated with increased risk for metastatic disease, prognostic significance of elevated preoperative CEA that normalized after resection is unknown. Objective To investigate whether patients with elevated preoperative CEA that normalizes after colon cancer resection have a higher risk of recurrence than patients with… CONTINUE READING