Association of PTPN22 haplotypes with type 1 diabetes in the Japanese population.

Abstract

The R620W polymorphism in the protein-tyrosine-phosphatase nonreceptor type 22 gene (PTPN22) confers susceptibility to type 1 diabetes (T1D) and other autoimmune diseases. This polymorphism is reportedly nonpolymorphic in the Asian population. Additional polymorphisms and specific haplotypes have also been associated with T1D, rheumatoid arthritis (RA) and… (More)
DOI: 10.1016/j.humimm.2010.05.016

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