Association of PPAR polymorphisms with cytokine levels in allergic rhinitis

  title={Association of PPAR polymorphisms with cytokine levels in allergic rhinitis},
  author={Magdolna Krasznai and Kinga Szaniszlo and Helga Kraxner and Eszter Vargha and Margit Kov{\'a}cs and Edit Kasz{\'a}s and Gyorgyi Mezei and Endre Cserh{\'a}ti and Zoltan Borocz and K{\'a}roly Cseh},
  journal={European Archives of Oto-Rhino-Laryngology},
Our aim was to study the association of Pro12Ala and exon6 C161T polymorphisms of PPARgamma and intron7 G/C polymorphisms of PPAR-alpha with clinical symptoms, peak nasal inspiratory flow values, serum soluble TNF-alpha, TNF-R1, Fas, Fas ligand and IgE concentrations in patients with seasonal allergic rhinitis during and after pollen season. We performed a follow-up study of 66 Hungarian patients with seasonal allergic rhinitis and 180 healthy referent subjects. We used PCR-RFLP technique and… CONTINUE READING


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